Guy C Brown Selected Research

Neoplasms (Cancer)

1/2021	The Phagocytic Code Regulating Phagocytosis of Mammalian Cells.
1/2019	Mechanisms of cell death induced by arginase and asparaginase in precursor B-cell lymphoblasts.
9/2017	Anti-CD47 antibodies induce phagocytosis of live, malignant B cells by macrophages via the Fc domain, resulting in cell death by phagoptosis.
8/2012	Primary phagocytosis of viable neurons by microglia activated with LPS or Aβ is dependent on calreticulin/LRP phagocytic signalling.

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Guy C Brown Research Topics

Disease

18	Necrosis 08/2014 - 12/2002
16	Inflammation (Inflammations) 04/2024 - 04/2005
11	Alzheimer Disease (Alzheimer's Disease) 04/2024 - 09/2006
8	Hypoxia (Hypoxemia) 12/2015 - 06/2003
5	Neuroinflammatory Diseases 01/2023 - 02/2012
5	Parkinson Disease (Parkinson's Disease) 01/2023 - 10/2013
5	Ischemia 02/2022 - 04/2003
4	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2021 - 01/2019
4	Neoplasms (Cancer) 01/2021 - 08/2012
3	Memory Disorders (Memory Loss) 01/2023 - 09/2019
3	Mitochondrial Diseases (Mitochondrial Disease) 08/2009 - 04/2003
2	Infections 04/2024 - 09/2019
2	Brain Ischemia (Cerebral Ischemia) 02/2022 - 10/2013
2	Stroke (Strokes) 02/2022 - 12/2021
2	Bacterial Infections (Bacterial Infection) 10/2021 - 09/2019
2	Amyloid Plaque 01/2021 - 09/2006
2	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (Leukemia, Pre B Cell) 01/2019 - 09/2017
2	Burkitt Lymphoma (Burkitt's Lymphoma) 01/2019 - 09/2017
1	Tauopathies 01/2023
1	Encephalitis (Encephalitis, Rasmussen) 01/2023
1	Brain Infarction 02/2022
1	Infarction (Infarctions) 02/2022
1	Communicable Diseases (Infectious Diseases) 01/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2021
1	Mental Disorders (Mental Disorder) 01/2021
1	Immune System Diseases (Immune Disorders) 01/2021
1	Liver Failure 09/2019
1	Acquired Immunodeficiency Syndrome (AIDS) 09/2019
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 09/2019
1	Sepsis (Septicemia) 09/2019
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2019
1	Lymphoma (Lymphomas) 01/2019
1	Disease Progression 04/2015
1	Traumatic Brain Injuries (Traumatic Brain Injury) 03/2014
1	Atrophy 10/2013

Drug/Important Bio-Agent (IBA)

10	Nitric Oxide (Nitrogen Monoxide)FDA Link 06/2010 - 10/2003
9	LipopolysaccharidesIBA 04/2024 - 10/2006
7	Proteins (Proteins, Gene)FDA Link 01/2021 - 08/2012
7	CaspasesIBA 01/2013 - 04/2003
6	Amyloid beta-PeptidesIBA 12/2021 - 09/2006
5	EndotoxinsIBA 04/2024 - 04/2005
5	Adenosine Triphosphate (ATP)IBA 12/2021 - 12/2002
5	Cytochromes c (Cytochrome c)IBA 01/2013 - 04/2003
5	Oxygen (Dioxygen)IBA 06/2010 - 06/2003
5	1- hydroxy- 2- oxo- 3,3- bis(2- aminoethyl)- 1- triazeneIBA 08/2009 - 12/2003
4	Amyloid (Amyloid Fibrils)IBA 04/2024 - 11/2011
4	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2023 - 09/2005
4	purinoceptor P2Y6IBA 01/2023 - 10/2021
3	Galectin 3 (LGALS3)IBA 04/2023 - 01/2019
3	CytokinesIBA 01/2023 - 06/2010
3	SynucleinsIBA 01/2023 - 03/2014
3	Glutamic Acid (Glutamate)FDA Link 01/2018 - 10/2007
3	Deoxyglucose (2 Deoxy D glucose)IBA 03/2014 - 01/2005
3	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 06/2010 - 06/2003
2	LigandsIBA 04/2023 - 01/2019
2	CalreticulinIBA 01/2022 - 08/2012
2	Complement System Proteins (Complement)IBA 12/2021 - 10/2018
2	Opsonin Proteins (Opsonins)IBA 12/2021 - 10/2018
2	Pattern Recognition ReceptorsIBA 01/2021 - 04/2015
2	ArginaseIBA 01/2019 - 04/2009
2	Peptides (Polypeptides)IBA 01/2019 - 09/2006
2	Peroxynitrous Acid (Peroxynitrite)IBA 12/2015 - 06/2003
2	Superoxides (Superoxide)IBA 12/2015 - 09/2005
2	milk fat globuleIBA 10/2013 - 04/2011
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 08/2009 - 04/2005
2	Nitric Oxide Synthase (NO Synthase)IBA 09/2005 - 04/2005
1	tau Proteins (tau Protein)IBA 01/2023
1	Syk KinaseIBA 01/2023
1	GalactosidasesIBA 01/2023
1	Endothelin-1 (Endothelin 1)IBA 02/2022
1	PhosphatidylserinesIBA 12/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	LipidsIBA 01/2021
1	N-Acetylneuraminic Acid (Sialic Acid)IBA 01/2021
1	Sialic Acid Binding Immunoglobulin-like LectinsIBA 01/2021
1	Apolipoproteins E (ApoE)IBA 09/2019
1	Apolipoprotein E4IBA 09/2019
1	Cytotoxins (Cytolysins)IBA 01/2019
1	Arginine (L-Arginine)FDA Link 01/2019
1	Asparaginase (Elspar)FDA Link 01/2019
1	Chloroquine (Aralen)FDA LinkGeneric 01/2019
1	EnzymesIBA 01/2019
1	CitrullineIBA 01/2019
1	ApolipoproteinsIBA 10/2018
1	Oxidants (Oxidizing Agents)IBA 01/2018
1	AntibodiesIBA 09/2017
1	Protein Kinases (Protein Kinase)IBA 12/2016
1	InterferonsIBA 03/2014
1	Protein Kinase CIBA 03/2014
1	Tetradecanoylphorbol AcetateIBA 03/2014
1	Interleukin-4 (Interleukin 4)IBA 03/2014
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 10/2013
1	c-Mer Tyrosine KinaseIBA 10/2013
1	Factor VIII (Coagulation Factor VIII)IBA 10/2013
1	Epidermal Growth Factor (EGF)IBA 10/2013
1	Transfer RNA (tRNA)IBA 10/2013
1	RotenoneIBA 10/2013
1	PesticidesIBA 10/2013

Therapy/Procedure

2	Therapeutics 01/2021 - 09/2017
1	Axotomy 01/2018